Spatial-Frequency Azimuthally Stable Cartography of Biological Polycrystalline Networks

Spatial-Frequency Azimuthally Stable Cartography of Biological Polycrystalline Networks

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A new azimuthally stable polarimetric technique processing microscopic images of optically anisotropic structures of biological tissues histological sections is proposed.It has been used as a generalized model of phase anisotropy definition of biological tissues by using superposition of Mueller matrices of linear birefringence and optical activity.The matrix element M44 has been chosen as the main information parameter, whose read more value is independent of the rotation angle of both sample and probing beam polarization plane.

For the first time, the technique of concerted spatial-frequency filtration has been used in order to separate the manifestation of linear birefringence and optical activity.Thereupon, the method of azimuthally stable spatial-frequency cartography of biological tissues histological sections has been elaborated.As the analyzing tool, complex statistic, correlation, and fractal analysis of coordinate distributions of M44 element has been performed.

The possibility of using the biopsy of the uterine wall tissue in order to differentiate benign (fibromyoma) and malignant bostik roll-cote (adenocarcinoma) conditions has been estimated.